Stem Cell Treatment for Stroke

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Patients with post-stroke syndrome can perhaps be treated with intravenous brain stem cells, oligodendrocytes to replace myelin, and neuron stem cells plus nerve cell growth factors. The latter can penetrate the blood brain barrier when they are placed in an emulsion solution. These cells migrate to areas of damaged tissue in the brain to enable recovery.

A sudden stroke is devastating and can lead to temporary or permanent impairment to speech, memory, sensation, and to motor neuron damage. The damage is caused by a bleeding, or a blocked blood vessel in the brain. This leads to localized areas of brain damage, along with loss of neurons and other brain cells, called glial cells.

There are areas in the adult brain that contain stem cells, however, their numbers are not enough to restore neurological function. On the other hand, umbilical cord blood has stem cells that have the ability to be transformed into precursor of different cells, including brain cells. Umbilical cord blood stem cells can form precursor progenitor brain stem cells, when they are placed in a culture with nerve growth factor, brain neurotrophic factor, glial growth factor, neurotrophin, vascular endothelial growth factor, and nutrients.

Patients with post-stroke syndrome--even those that have had it for many years—can perhaps be treated with intravenous brain stem cells, oligodendrocytes to replace myelin, and neuron stem cells plus nerve cell growth factors. The latter can penetrate the blood brain barrier when they are placed in an emulsion solution. These cells migrate to areas of damaged tissue in the brain to enable recovery.

An alternate method is to introduce neuron brain stem cells plus the growth factors into the central nervous system and the spinal canal. Patients with a history of stroke and carotid stenosis are also given vascular endothelial growth factor; CD 34+ and CD133+ progenitor cells.
No effective therapy currently exists for stroke patients with brain damage, so any treatment that offers a chance of improvement is very good news indeed. The discovery of stem cell treatment brings new hope.

 

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