Latest News - Research

April 25, 2010 | New England Journal Of Medicine

A 40-year-old Caucasian male with newly diagnosed acute myeloid leukemia (FAB M4 subtype, with normal cytogenetic features) arrive at the hospital. HIV-1 infection had been diagnosed more than 10 years before. The patient had been treated with highly active antiretroviral therapy (HAART) (600 mg of efavirenz, 200 mg of emtricitabine, and 300 mg of tenofovir per day) for 4 years. During that time no illnesses associated with the acquired immunodeficiency syndrome (AIDS) were observed.

April 22, 2010

Scripps Research Institute scientists have solved the problem of why human embryonic stem cells are so difficult to culture in the lab. This new insight will provide scientists with helpful new techniques to move closer to a time when stem cells can be used for therapeutic purposes.
The research will appear in the journal Proceedings of the National Academy of Sciences (PNAS) during April 2010.

March 23, 2010 | physorg.com Duke University Medical Center

Researchers believe that umbilical cord blood may serve as a universal source of available stem cells for patients who need a stem cell transplant. However, the number of stem cells in cord blood is limited, so there they must develop a method to increase the amount of cord blood stem cells for transplantation purposes. John Chute, M.D., a stem cell transplant specialist and cell biologist at says that unfortunately, no soluble growth factors have yet been identified that have been proven to expand human stem cells for therapeutic uses.

March 2, 2010 | UCLA Newsroom

UCLA AIDS Institute researchers have successfully removed CCR5 from human cells. CCR5 is a cell receptor to which HIV-1 binds but it is a receptor which the human body does not need. People who naturally lack this CCR5 receptor have been found to be resistant to HIV.

Employing a humanized mouse model, the researchers transplanted a small RNA molecule called a short hairpin RNA (shRNA), which induced RNA interference into blood stem cells in order to inhibit the expression of CCR5 in immune cells.

February 11, 2010 | Prague Daily Monitor

To create stem cell from body cells, they must be reprogrammed. However, the small RNA that are contained in those body cells had prevented their reprogramming - until now.

Czech and American scientists have uncovered certain regularities in the genesis of mammalian embryos that may simplify the production of stem cells taken from body cells.

October 25, 2009 | Genetic Engineering and Biotechnology News

Cellerix and Gamida Cell have announced plans to collaborate on a feasibility study  to evaluate the potential of combining the former’s cell-based therapeutics with the latter’s stem cell expansion technologies. Cellerix, a Spanish company, is developing cell-based medications using expanded adult stem cells obtained from adipose tissue. Gamida Cell, based in Israel, is working to develop technologies to expand, ex vivo, populations of stem or progenitor cells that display increased in vivo homing and engraftment activities.

October 21, 2009 | ALS Association

The FDA has recently approved the trial use of stem cells on human subjects suffering from Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig’s disease). The study will be carried out by Neuralstem Inc. and will examine the safety of Neuralstem’s cells as well as the surgical procedures and the devices required for injections directly into the spinal cord’s grey matter. Initially, 12 patients will receive five to ten injections of stem cells into the lumbar area of the spinal cord. After the procedure, the patients will be examined at regular intervals.

September 23, 2009 | Medical News Today

University of Utah medical ethics expert Jeffrey R. Botkin will chair a federal panel that will review scientists' requests to conduct government-funded research using embryonic stem cells left over from couples who used "test-tube fertilization" to have babies.

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